Fine-tuning treatment for triple-negative breast cancer

Researchers at the University of Queensland may have found a way to improve treatment of triple-negative breast cancer. The team found that triple-negative breast tumours with the highest energy usage respond best to chemotherapy because the ‘recycling stations’ that deal with metabolic by-products, called proteasomes, also make cancer more ‘visible’ to the immune system. Lead […]

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First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes

Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study, published in Diabetes, also revealed one protein—called PRDX4—that may be essential for proinsulin folding and insulin production. The research suggests that boosting […]

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Molecular pair offers potential for Parkinson’s treatment, study finds

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson’s disease, a study by Nanyang Technological University, Singapore (NTU Singapore) and Harvard University has found. Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting 7 to 10 million people worldwide. […]

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